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We are searching for an outstanding Scientist I to join the Gene Therapy team in San Diego, CA.
This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo and ex vivo genome editing and gene therapy applications. This person will be engaged in the analysis of novel nanoparticle-based pharmaceuticals.
Responsibilities May Include But Are Not Limited To
- Work at the direction of Analytical scientists to quantitate lipid nanoparticles (LNPs) encapsulating nucleic acids
- Analyze raw materials for LNP formulations
- Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety
- Maintain detailed records of analytical data
- Interface directly with other functional teams
- Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)
- Masters or Bachelors degree with 2+ years experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or related scientific discipline (an equivalent combination of education and experience may be considered).
- Practical experience using analytical methods such as RiboGreen, Dynamic Light Scattering (DLS), and Zeta potential measurement is strongly preferred
- Prior experience with High-Performance Liquid Chromatography (HPLC) is preferred
- Experience and proficiency with other analytical techniques will be considered
- Proficiency at formulating buffers is required
- Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team
- Ability to be a team player, multitask and work on multiple projects at once, and excel in a collaborative work environment.
- Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable
- Excellent oral and written communication skills
